HEPAMERZ

Hepa-Merz® (L-ornithine and L-aspartic acid (LOLA).

Available as Hepa-Merz® 150mg Tablets and Hepa-Merz® Granules

Hepa-Merz® (LOLA) increases ammonia detoxification in two ways:

  • Liver (periportal hepatocytes): activation of the urea cycle in the liver by making available the metabolic substrate ornithine which activates the enzyme carbamoyl phosphate synthetase in the cirrhotic liver1
  • Brain, muscle, liver (perivenous cells), the substrates ornithine and aspartate promote the formation of glutamate which results in stimulation of ammonia detoxification via glutamine synthesis1

Hepa-Merz is indicated for the treatment of liver disorders that accompany, or are secondary to hepatic detoxification impairment (e.g., liver cirrhosis) with symptoms of latent and manifest hepatic encephalopathy.

  • Ideal Supportive and Maintenance Therapy in Patients with Liver Disorders
  • Improves hepatic injury
  • Controls oxidative damage
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